Rubidium rb-82
Cardiogen, Ruby-fill (rubidium rb-82) is a small molecule pharmaceutical. Rubidium rb-82 was first approved as Cardiogen-82 on 1989-12-29.
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Commercial
Therapeutic Areas
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| cardiogen-82 | New Drug Application | 2024-06-12 |
| ruby-fill | New Drug Application | 2020-10-20 |
Indications
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Agency Specific
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Patent Expiration
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HCPCS
Code | Description |
|---|---|
| A9555 | Rubidium rb-82, diagnostic, per study dose, up to 60 millicuries |
Clinical
Clinical Trials
20 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Coronary artery disease | D003324 | — | I25.1 | 1 | — | 1 | 2 | 8 | 12 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | 1 | — | 1 | 1 | 4 | 7 |
| Myocardial infarction | D009203 | EFO_0000612 | I21 | 1 | — | — | 1 | 1 | 3 |
| Infarction | D007238 | EFO_0009463 | — | 1 | — | — | 1 | 1 | 3 |
| Coronary disease | D003327 | — | — | — | — | 1 | 1 | 1 | 3 |
| Heart failure | D006333 | HP_0001635 | I50 | — | — | — | 1 | — | 1 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | 1 | — | 1 |
| Pulmonary hypertension | D006976 | EFO_0001361 | I27.20 | — | — | — | 1 | — | 1 |
| Cardiomyopathies | D009202 | EFO_0000318 | I42 | — | — | — | 1 | — | 1 |
| Pulmonary arterial hypertension | D000081029 | — | — | — | — | — | 1 | — | 1 |
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart diseases | D006331 | EFO_0003777 | I51.9 | 2 | — | — | — | 4 | 6 |
| Sarcoidosis | D012507 | EFO_0000690 | D80-D89 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Radiation exposure | D000069079 | — | — | — | — | — | — | 2 | 2 |
| Left ventricular dysfunction | D018487 | — | — | — | — | — | — | 1 | 1 |
| Colorectal neoplasms | D015179 | — | — | — | — | — | — | 1 | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | — | — | 1 | 1 |
| Head and neck neoplasms | D006258 | — | — | — | — | — | — | 1 | 1 |
| Esophageal neoplasms | D004938 | — | C15 | — | — | — | — | 1 | 1 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | — | — | — | — | 1 | 1 |
| Myocardial reperfusion | D015425 | — | — | — | — | — | — | 1 | 1 |
| Ischemia | D007511 | EFO_0000556 | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Rubidium rb-82 |
| INN | — |
| Description | Cardiogen, Ruby-fill (rubidium rb-82) is a small molecule pharmaceutical. Rubidium rb-82 was first approved as Cardiogen-82 on 1989-12-29. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | [82Rb] |
Identifiers
| PDB | — |
| CAS-ID | 14391-63-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297424 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
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Trends
PubMed Central
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Additional graphs summarizing 116 documents
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Safety
Black-box Warning
Black-box warning for: Cardiogen-82, Ruby-fill
Adverse Events
Top Adverse Reactions
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135 adverse events reported
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